My CV

Publications

First author

Arribas YA, Baudon B, Rotival M, Suárez G, Bonté PE, Casas V, Roubert A, Klein P, Bonnin E, Mchich B, Legoix P, Baulande S, Sadacca B, Diharce J, Waterfall JJ, Etchebest C, Carrascal M, Goudot C, Quintana-Murci L, Burbage M, Merlotti A, Amigorena S. Transposable element exonization generates a reservoir of evolving and functional protein isoforms. Cell. 2024 Dec 26;187(26):7603-7620.e22. doi: 10.1016/j.cell.2024.11.011. PMID: 39667937.

Bonté PE*, Arribas YA*, Merlotti A, Carrascal M, Zhang JV, Zueva E, Binder ZA, Alanio C, Goudot C, Amigorena S. Single-cell RNA-seq-based proteogenomics identifies glioblastoma-specific transposable elements encoding HLA-I-presented peptides. Cell Rep. 2022 Jun 7;39(10):110916. doi: 10.1016/j.celrep.2022.110916. PMID: 35675780. (*equal contribution)

Merlotti A*, Sadacca  B*, Arribas YA*, Houy A, Ngoma M, Goudot C, Rocañín-Arjó S, Lalanne A, Seguin-Givelet A, Lefevre M, Burbage M, Oliveira G, Loew D, Carrascal M, Wu CJ, Lantz O, Stern MH, Girard N, Waterfall JJ, Amigorena DS. Noncanonical splicing junctions between exons and transposable elements represent a source of immunogenic recurrent neo-antigens in patients with lung cancer. Sci Immunol. 2023 Feb 3;8(80):eabm6359. doi: 10.1126/sciimmunol.abm6359. PMID: 36735774. (*equal contribution)

Other publications

Burbage M*, Rocañín-Arjó A*, Baudon B, Arribas YA, Merlotti A, Rookhuizen DC, Ye M, Houy A, Burgdorf N, Suarez G, Gros M, Sadacca B, Carrascal M, Garmilla A, Bohec M, Baulande S, Lombard B, Loew D, waterfall JJ, Stern MH, Goudot C, Amigorena DS. Epigenetically controlled tumor antigens derived from splice junctions between exons and transposable elements. Sci Immunol. 2023 Feb 3;8(80):eabm6360. doi: 10.1126/sciimmunol.abm6360. PMID: 36735776.

López Malizia A, Merlotti A, Bonté PE, Sager M, Arribas Y, Goudot C, Erra Díaz F, Pereyra-Gerber P, Ceballos A, Amigorena S, Geffner J, Sabatte J. Clusterin protects mature dendritic cells from reactive oxygen species mediated cell death. OncoImmunology, 2024. doi: 10.1080/2162402X.2023.2294564

Cocozza F, Martin-Jaular L, Lippens L, Di Cicco A, Arribas YA, Ansart N, Dingli F, Richard M, Merle L, Jouve San Roman M, Poullet P, Loew D, Lévy D, Hendrix A, Kassiotis G, Joliot A, Tkach M, Théry C. Extracellular vesicles and co-isolated endogenous retroviruses from murine cancer cells differentially affect dendritic cells. EMBO J. 2023 Dec 11. doi: 10.15252/embj.2023113590. PMID: 38073509.

Bonté PE, Metoikidou C, Heurtebise-Chretien S, Arribas YA, Sutra Del Galy A, Ye M, Niborski LL, Zueva E, Piaggio E, Seguin-Givelet A, Girard N, Alanio C, Burbage M, Goudot C, Amigorena S. Selective control of transposable element expression during T cell exhaustion and anti-PD-1 treatment. Sci Immunol. 2023 Oct 27. doi: 10.1126/sciimmunol.adf8838. PMID: 37889984. 

Aran A, Peg V, Rabanal RM, Bernadó C, Zamora E, Molina E, Arribas YA, Arribas J, Pérez J, Roura-Mir C, Carrascal M, Cortés J, Martí M. Epstein-Barr Virus+ B Cells in Breast Cancer Immune Response: A Case Report. Front Immunol. 2021 Nov 16;12:761798. doi: 10.3389/fimmu.2021.761798. PMID: 34868006; PMCID: PMC8637110.

Patents

Amigorena, S; Burbage, M; Houy, A; Waterfall, J; Stern, MH; Sadacca, B; Merlotti, A; Arribas, Y. Immunotherapy targeting tumor neoantigenic peptides. WO2021/043804A1. EP2020074429W. 2020.

Amigorena, S; Burbage, M; Houy, A; Waterfall, J; Stern, MH; Sadacca, B; Merlotti, A; Arribas, Y; Goudot, C. Tumor neoantigenic peptides and uses thereof. WO2022/189639A1. EP21305302A. 2021.

Amigorena, S; Burbage, M; Houy, A; Waterfall, J; Stern, MH; Sadacca, B; Merlotti, A; Goudot, C; Lopez-Lastra, S; Arribas, Y. Transmembrane neoantigenic peptides. WO2022/189620A1. EP21305296A. 2021.

Amigorena, S; Burbage, M; Houy, A; Waterfall, J; Stern, MH; Sadacca, B; Merlotti, A; Arribas, Y; Goudot, C. Tumor neoantigenic peptides. WO 2022/189626A2. EP21305299A. 2021.

Amigorena, S; Merlotti, A; Goudot, C; Bonte PE; Arribas, Y. Immunotherapy targeting tumor transposable element derived neoantigenic peptides in glioblastoma. 2022.

Oral communications and poster presentations

2025: Invited speaker. Winter meeting - Catalan Society of Immunology (Barcelona)

2024: Oral communication. Latin American and Caribbean Association of Immunology (Buenos Aires)

2024: Oral communication. European Congress of Immunology (Dublin)

2023: Poster. International Union of Immunological Societies (Cape Town)

2022: Flash talk and poster. HUPO-Human Immunopeptidome Project (Oxford). Best Poster Award.

2022: Oral communication. 2nd Meeting of Spanish, French and Portuguese Proteomics Societies (Portugal)

2020: Poster. VIII Congress of Sociedad Española de Proteómica (Oviedo)

2019: Oral communication and poster. EMBO Antigen processing and presentation 10 (Paris)

2018: Poster. B-Debate: Clinical Proteomics (Barcelona)

2018: Poster. 5th European Congress of Immunology (Amsterdam)

2018: Poster. Cellular Biology, Physiology and Immunology UAB journeys (Barcelona). Best Poster Award.

2017: Poster. SPSAS on Mass Spectrometry-based Proteomics (Sao Paulo, Brazil). Best Poster Award.

2017: Poster. Cellular Biology, Physiology and Immunology UAB journeys (Barcelona)

2013: Oral communication. XIth SCAR Biology Symposium (Barcelona)

Fellowships & Honors

2019: Sociedad Española de Proteómica (SeProt)

2019-2022: Ligue National Contre Le Cancer

2022-2023: Fondation ARC

2024: Best PhD thesis of the Spanish Society of Proteomics

References

Sebastian Amigorena, PhD Laboratory of Immunity and Cancer, U932, Institut Curie, Paris. (sebastian.amigorena@curie.fr)

Dolores Jaraquemada, PhD, Prof. Immunology Laboratory of Cellular Immunology, Institut de Biotecnologia i Biomedicina (IBB), Autonomous University of Barcelona. (dolores.jaraquemada@uab.cat)

Montserrat Carrascal, PhD CSIC-UAB Proteomics Laboratory, Faculty of Medicine, Autonomous University of Barcelona (UAB). (montserrat.carrascal.csic@uab.cat)

Joshua Waterfall, PhD Laboratory of Integrative Functional Genomics in Cancer, U830, Institut Curie, Paris. (joshua.waterfall@curie.fr)